Bis(tri-tert-butylphosphine)palladium(0)
CAS 53199-31-8
Pd(P(t-Bu)₃)₂ is an electron-rich, coordinatively unsaturated Pd(0) complex used where conventional Pd/phosphine systems fail — most notably cross-couplings of unactivated aryl chlorides at low catalyst loading.
Typical specification
| Molecular formula | C₂₄H₅₄P₂Pd |
|---|---|
| Molecular weight | 511.06 |
| Assay (Pd complex) | ≥ 98% |
| Palladium content | 20.3 – 21.0% |
| Appearance | Off-white to pale-yellow crystalline powder |
| Melting point | ~102 °C (dec.) |
| Solubility | Soluble in THF, toluene, benzene; decomposes in chlorinated solvents over time |
| Packaging atmosphere | Argon |
| HS code (export) | 2843900099 |
Lot-specific COA issued with every shipment. SDS and ICP elemental impurity data available on request.
Where Pd(P(t-Bu)₃)₂ is used
Cross-coupling of aryl chlorides
The strongly σ-donating, bulky P(t-Bu)₃ ligands promote oxidative addition into C–Cl bonds, enabling Suzuki–Miyaura and Negishi couplings of inexpensive aryl chloride substrates that are unreactive toward Pd(PPh₃)₄, often at 0.5–1 mol% loading and mild temperature.
Buchwald–Hartwig amination
A workhorse pre-catalyst for C–N bond formation in API route development — couplings of aryl halides with primary and secondary amines, including sterically hindered partners, without a separate ligand charge.
OLED intermediate synthesis
Used in carbazole, triarylamine and fluorene chemistry for hole-transport and emitter intermediates, where low residual Pd and reproducible activity matter for downstream sublimation-grade purity.
Storage and shipping
Storage. Store cold (2–8 °C) under inert gas; air- and moisture-sensitive. Handle under nitrogen or argon.
Shipping. Ships under inert atmosphere in sealed ampoules or septum bottles. Transport classification confirmed per shipment.
Packaging. 1 g · 5 g · 25 g · 100 g · Bulk (custom, under argon)
Synonyms
- Pd(t-Bu3P)2
- Bis(tri-t-butylphosphine)palladium
- Palladium bis(tri-tert-butylphosphine)
- Pd[P(tBu)3]2
- Tri-tert-butylphosphine palladium(0) complex
Frequently asked questions
How is Pd(P(t-Bu)₃)₂ priced?
Quotes are built from the day's palladium fixing plus a fabrication charge, so pricing tracks the metal market transparently. Lock-in against a specific fixing date is available on confirmed orders.
Do you take back spent catalyst?
Yes. We operate a palladium recovery loop: spent catalyst and Pd-containing residues can be assayed and credited against your next purchase, which lowers total cost of ownership versus one-way supply.
What documentation ships with the product?
Every lot ships with a certificate of analysis (assay, Pd content, appearance) and an SDS. Elemental impurity data (ICP) is available for pharmaceutical customers on request.
What is the typical lead time?
Gram to 100 g quantities normally ship within 5–7 working days from Shanghai. Larger or recurring volumes are scheduled against your forecast.